The Synthesis of 2, 3-Dimethyl-1, 2, 3, 4, 10, 11-hexahydrofluorenylamine
نویسندگان
چکیده
منابع مشابه
2-(10′,10′-Dimethyl-3′-sulfanylidene-4′-azatricyclo[5.2.1.01,5]decan-2′-yl)-10,10-dimethyl-4-azatricyclo[5.2.1.01,5]decane-3-thione
The title compound, C28H40N2O2S2, was obtained as a minor product from an anti-aldol reaction between the corresponding N-propionyl-thiol-actam and benzaldehyde. The asymmetric unit contains one half-molecule, which is completed by inversion symmetry. The molecule displays a nearly eclipsed conformation along the central C-C bond with a C-C-C-C- torsion angle of 20.4 (3)°.
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A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...
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ژورنال
عنوان ژورنال: NIPPON KAGAKU KAISHI
سال: 1939
ISSN: 0369-4208,2185-0909
DOI: 10.1246/nikkashi1921.60.18